Projects

The ecological niche occupied by a fungal species, its pathogenicity and its usefulness as a microbial cell factory to a large degree depends on its secretome. Protein secretion usually requires the presence of a N- terminal signal peptide (SP) and by scanning for this feature using available highly accurate SP-prediction tools, the fraction of potentially secreted proteins can be directly predicted. However, prediction of a SP does not guarantee that the protein is actually secreted and current ...

Enhanced production of BIOtech personal CARE antioxidants from dairy side-streams- Lactobionic by Pseudomonas taetrolens

Co-Culture for improved lignocellulose fractionation and elicitation of enzymatic activies - Omics on co-culture of trichoderma reesei or Phanerochaete chrysosporium

A collection of protocols that have been curated and validated

Cyanotoxins Study using Fluorescence Correlation Spectroscopy

Structural colour is widely found in nature and is defined by at least partially ordered nanostructures which interact with light to create vivid, angle-dependent colour. Structural colour (SC) is quite distinct from chemical pigments and offers superior properties (intensity, resistance to bleaching, advanced optical effects) compared to pigments and dyes. SC is familiar to us, for example in the way the feathers of the peacock catch the light. SC was observed by Hook and Newten in the 17th ...

In this project we have, as general objective, the screening of few extremozymes from the thermophilic/anaerobic Caldicoprobacter algerensis strain [1] using genomic approach. The major specific goal of this project is the determination of the whole genome sequence of this strain followed by sequence assembly and annotation. We will then exploit the obtained sequence to identify potential ORFs encoding extremozymes with industrial interest. A particular interest will be done for CAZymes (Xylanase, ...

Optimisation of production of flavin-containing oxidoreductases for industrial application

High-resolutions fluxomics of industrial cyanobacteria

Infant formula milk tries to mimic human milk as closely as possible, since it is well-known that breast milk has considerable implications in the development of the infant intestinal microbiota in the first years of life. Human milk is considered to be unique in terms of its content of complex oligosaccharides. They are abundant in human milk and their role in the development of intestinal flora blocking the attachment of pathogens and modulating immune system of the infant make them of great ...

Default library of IBISBA related information, The contents will be categorized later.

Microalgal lipids are valuable compounds of growing interest for health applications in food, feed and pharmaceutical industries. Especially, very long-chain polyunsaturated fatty acids (VLC-PUFAs) such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (ARA) are essential dietary components for animals and humans. Production of such nutritional and functional lipids from microalgae is a promising strategy, but still faces some challenges to make it cost-efficient. ...

Multienzymatic oxidation of glycerol

Construction of a P. putida KT2440 producing cis,cis-muconate from glucose, benzoate, or p-coumarate

Calidris Bio aims to bring a technology to the market to produce microbial protein for feed and food purposes. Calidris Bio is developing a production process consisting of fermentation and conditioning of the microbial biomass. The fermentation process was optimised at lab-scale (2L fed-batch and continuous fermentation) with a productivity of 10g/L/h. The next step is to scale-up the process to pilot scale. A concomitant life cycle analysis will be performed to pinpoint hotspots thus improving ...

Plant-based bio-encapsulation strategies for oral veterinary vaccines

Expression of a PET-hydrolysing polyesterase in Pseudomonas putida

Innovative methanol free promoter comparison for Pichia pastoris for scalable bioprocesses

A collection of announcements and documents

A project for templates for templates for data, protocols etc. and for their documentation and examples.

Prof. Pinar Calik, from the Ankara University (Turkey) is one of the first IBISBA users, who was granted access to IBISBA facilities for her project on P. pastoris called TRANSCRIPTPROM. We were pleased to have prof. Pinar Calik, Head of the Chemical Engineering Department of the Ankara University (Turkey), at the mid-term EC review sharing her experience as one of the first IBISBA users.

Thanks to IBISBA prompt response after the submission of the application, and the network of IBISBA facilities, ...

Farming of shellfish and seaweed is still new in Denmark and on a commercial scale is primarily limited to the production of longline mussels. It is mainly for mussels, that aquaculture production rely on natural spatfall. For all other species, such as oysters and macroalgae, hatcheries for the production of spat or seeding material are necessary. A major bottleneck in all bivalve hatchery is the food production, both in term of quantity and quality.

The native European flat oysters, is a key ...

The collection of protocols that have not yet been curated by IBISBA WP6

Lipase cell-surface display in Yarrowia lipolytica for direct biofuel production